Effects of Angelica Oil on Germ Tube Formation and Adhesion of Candida albicans

Objective: To investigate the effects of angelica oil on Candida albicans germ tube formation and adhesion of Candida albicans to human oral epithelial cells.Methods: Candida albicans suspension and mixed suspension of Candida albicans with human oral epithelial cells were incubated with various concentrations of angelica oil(100,50,10 mg/L) respectively.The rates of germ tube formation and Candida albicans adhering to human oral epithelial cells were counted under microscope.Results: All concentrations of angelica oil inhibited Candida albicans germ tube formation and adhesion of Candida albicans to oral epithelial cells.Conclusions: Angelica oil could inhibit Candida albicans germ tube formation and adhesion of Candida albicans to oral epithelial cells.