Effects of percutaneous coronary intervention on brain natriuretic peptide and ventricular remodeling in patients with ST elevation myocardial infarction

Objective To study the effects of percutaneous coronary intervention (PCI) on brain natriuretic peptide (BNP) and ventricular remodeling in patients with ST elevation myocardial infarction (STEMI). Methods Ninety-six patients with STEMI were divided into the observation group (n=47) and the control group (n=49), and the observation group were given primary PCI, while the control group were given elective PCI. BNP and ventricular remodeling were compared between the two groups, and the short-term prognosis were observed. Results There was no significantly difference in BNP, LVEDd and LVEF between the two groups before PCI, but BNP, LVEDd were significantly reduced after PCI (P0.01 or P0.05), and LVEF was significantly increased (P0.01), and the observation group were significantly better than the control group after PCI (P0.01). There was no significant difference in cardiac mortality between the two groups. Conclusion PCI has reliable efficacy in patients with STEMI, the BNP and the ventricular remodeling changed significantly in patients accepted primary PCI, but there is no significantly effect of the timing of PCI on the short-term prognosis.