Analysis of the drug-resistance of Neisseria gonorrhoeae to six types of antibiotics in Huizhou

Objective To survey the antibiotic resistance and the prevalence of penicillinase-producing Neisseria gonorrhoeae(PPNG) and tetracycline resistant Neisseria gonorrhoeae(TRNG) in Huizhou.Methods Minimum inhibitory concentrations(MIC) to penicillin G,tetracycline,ciprofloxacin,azithromycin,ceftriaxone and spectinomycin were determined by using agar dilution methods,and β-lactamase was determined by paper iodine quantitative method.Results 51 strains(37.2%) of PPNG,82 strains(59.9%)of TRNG,137 strains(100.0%) resistant to ciprofloxacin and 41 strains(29.9%) resistant to azithromycin were detected in 137 strains.There was no ceftriaxone or spectinomycin resistant strain.Conclusion Ceftriaxone and spectinomycin could be the first choice to treat patients with Neisseria gonorrhoeae infection and it could be important to survey the antibiotic resistance of Neisseria gonorrhoeae.