A Clinical Observation of Ramipril, Digoxin, Diuretic Combine Medication on Treatment of Chronic Con-gestive Heart Failure

Objective: To Compare the effects of Ramipril, Digoxin and Diuretic with Digoxin and Diuretic on cardiac function, heart rate, cardio-thoracic ratio and left ventricular ejection fraction (LVEF) in chronic congestive heart failure (CHF) patients. Methods: Sixty patients were allocated randomly into two groups , one group received Ramipril, Digoxin and Diuretic, and the other group received Digoxin and Diuretic as control group, for 12 weeks. Results: The heart rate were lower significantly in both groups after treatment of one week (P0.01), the cardio-thoracic ratio reduced, LVEF increased significantly(P0.05) in ramipril group after 12 weeks treatment, while no significant changes in control group (P0.05). Conclusions: Ramipril, Digoxin and Diuretic is more effective than Digoxin and Diuretic treatment on heart rate reduction, cardio-thoracic ratio decrease, LVEF increase in CHF patiens.