Research Progress in Relationship between Gelatinase and Carcinoma
FU Leng-x
Abstract
FU Leng-x
Abstract
Gelatinase is one of the most important subtype of matrix metalloproteinase,including MMP2 and MMP9.In recent years,awareness of MMP2,MMP9 and their inhibitors have done a great deal of research to understand their physiological and pathological significance.At present,the fine structure and functional analysis of MMP-based MMP inhibitors designed have been widely applied in animal models of tumor metastasis as well as human cancer clinical researches.
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Gelatinase is one of the most important subtype of matrix metalloproteinase,including MMP2 and MMP9.In recent years,awareness of MMP2,MMP9 and their inhibitors have done a great deal of research to understand their physiological and pathological significance.At present,the fine structure and functional analysis of MMP-based MMP inhibitors designed have been widely applied in animal models of tumor metastasis as well as human cancer clinical researches.
Key concepts: MMP2, Gelatinase, MMP9, Matrix metalloproteinase, Gelatinase A, Metastasis, Pathological, Cancer