The Application of Sufentanil in Laparoscopic Cholecystectomy

Objective:To observe the effect of sufentanil for laparoscopic cholecystectomy on hemodynamic and anesthesia recovery condition.Methods:Sixty ASA I~II patients(36~72years old) underwent selective laparoscopic cholecystectomy were divided into two groups randomly with sufentanil(group SF,n=30) and fentanyl(group F,n=30).SBP,DBP,HR were detected at different time points which including times before induction(T0),immediately intubation(T1),before pneumoperitoneum(T2),5 minutes after pneumoperitoneum(T3)(the pressure of CO2 pneumoperitoneum was 13mmHg),meanwhile,anesthesia recovery condition were recorded at four different stages.Results:Sixty completed trial.The using of equivalent dose of sufentanil or fentanyl are suitable in laparoscopic cholecystectomy,SBP,DBP,HR in group SF was significantly less than those in the group F(P0.05).The spontaneous breathing of both groups have no significant difference(P0.05).The first time to wake up in group SF were longer than those of group F(P0.05),but awake and extubation time was much shorter(P0.05).Conclusion:Sufentanil could be used in laparoscopic cholecystectomy that has lighten stress reaction,maintained the stabilization of haemodynamics,with rapidly and timely anesthesia recovery.