Differential diagnosis value of multiple indexes in tuberculous and malignant pleural effusion

Objective To investigate the differential diagnostic values of the levels of lactate dehydrogenase(LDH),adenosine deaminase(ADA),C-reactive protein(CRP) and tuberculosis antibody(TB-Ab) in malignant and tuberculous pleural effusion.Methods 113 cases with differential diagnostic pleural effusion were divided into tuberculous pleural effusion and malignant pleural effusion groups.The levels of LDH,ADA,CRP and TB-Ab were detected and statistically analyzed in the two groups.Results The concentration of ADA,CRP and the positive rate of TB-Ab in tuberculous pleural effusion groups were significantly higher than those of malignant pleural effusion group(P0.01).The concentration of LDH in malignant pleural effusion group was higher than that of tuberculous pleural effusion group(P0.01).Conclusion The determination of LDH,ADA,CRP and TB-Ab in pleural effusion has important clinical value for identification malignant and tuberculous pleural effusion.