Drug Resistance of Mycobacterium Tuberculosis in Mianyang

Objective To understand the situation of drug resistant Mycobacterium tuberculosis in Mianyang,provide evidence for tuberculosis control.Methods Scaling method was applied to test the drug resistant of isoniazide(INH),rifampicin(RFP),streptomycin(SM),and ethambutol(EMB) for 79 strains of Mycobacterium tuberculosis.Results Totally 17 drug resistant Mycobacterium tuberculosis strains were detected.The total drug resistance rate,poly-resistance rate and multi-drug resistance rate was 21.52%,12.66% and 6.33% respectively.The initial drug-resistance rate and the acquired drug-resistance rate was 18.64% and 30.00% respectively.The sequence of single drug-resistance was INHSMRFPEMB,the drug-resistance rate was 15.19%,12.66%,7.59% and 7.14% respectively.There was no statistical significance in sex groups and age groups.Conclusion The local drug-resistance rate of Mycobacterium tuberculosis in Mianyang was lower than the national average level.It is suggested that drug-resistance mornitoring should be strengthened for guiding reasonable clinical prescription.