2014Wuhan Daxue xuebao. Yixue banRequires access

Curative Effect of Combined Esmolol and Amiodarone on Ventricular Electrical Storm in Patients with Acute Coronary Syndrome

Zeng Bi

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Abstract

Objective:To observe the curative effect of combined esmolol and amiodarone on ventricular electrical storm in the patients with acute coronary syndrome(ACS).Methods:Forty-five cases of ventricular electrical storm in the patients with ACS were randomly divided into two groups as amiodarone group(n=30)and esmolol plus amiodarone group(n=25).The success rate of electroversion and adverse reactions were recorded,systolic blood pressure(SBP),heart rate(HR),and QTd were measured and compared between the two groups.Results:The success rate of terminating VT and VF was significantly higher in combined group than in amiodarone group(92%vs.65%,P0.05).The HR and the QTd in combined group were lower than those in amiodarone group(P0.05).Conclusion:The intravenous injection of combined esmolol and amiodarone is a safe and effective treatment strategy for treating ventricular electrical storm in the patients with ACS.

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What this paper is about

Objective:To observe the curative effect of combined esmolol and amiodarone on ventricular electrical storm in the patients with acute coronary syndrome(ACS).Methods:Forty-five cases of ventricular electrical storm in the patients with ACS were randomly divided into two groups as amiodarone group(n=30)and esmolol plus amiodarone group(n=25).The success rate of electroversion and adverse reactions were recorded,systolic blood pressure(SBP),heart rate(HR),and QTd were measured and compared between the two groups.Results:The success rate of terminating VT and VF was significantly higher in combined group than in amiodarone group(92%vs.65%,P0.05).The HR and the QTd in combined group were lower than those in amiodarone group(P0.05).Conclusion:The intravenous injection of combined esmolol and amiodarone is a safe and effective treatment strategy for treating ventricular electrical storm in the patients with ACS.

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Available abstract

Objective:To observe the curative effect of combined esmolol and amiodarone on ventricular electrical storm in the patients with acute coronary syndrome(ACS).Methods:Forty-five cases of ventricular electrical storm in the patients with ACS were randomly divided into two groups as amiodarone group(n=30)and esmolol plus amiodarone group(n=25).The success rate of electroversion and adverse reactions were recorded,systolic blood pressure(SBP),heart rate(HR),and QTd were measured and compared between the two groups.Results:The success rate of terminating VT and VF was significantly higher in combined group than in amiodarone group(92%vs.65%,P0.05).The HR and the QTd in combined group were lower than those in amiodarone group(P0.05).Conclusion:The intravenous injection of combined esmolol and amiodarone is a safe and effective treatment strategy for treating ventricular electrical storm in the patients with ACS.

Key concepts: Esmolol, Amiodarone, Medicine, Cardiology, Internal medicine, Anesthesia, Adverse effect, Heart rate

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Curative Effect of Combined Esmolol and Amiodarone on Ventricular Electrical Storm in Patients with Acute Coronary Syndrome — Research Paper | ScholarLens