Evaluation of Tramadol for Patient-controlled Intravenous Analgesia after Cesarean Section

【Objective】 To evaluate the effects and side effects of tramadol and morphine used for patient-controlled intravenous analgesia(PCIA).【Methods】A single-center,randomized double-blind study of ASAⅠ~Ⅱ 60 patients undergoing cesarean section was performed.The patients were divided into there groups: tramadol group(group T,n=20),morphine group(group M,n=20)and tramadol+ondansetron(group TO,n=20).The study lasted for 24 hours.Heart rate,blood pressure,respiration rate,VAS,Prince Henry score(PHS) and rate of side effects such as nausea and vomiting were observed.The consumption of analgetics in 24 hours was recorded.【Results】 The score of VAS and PHS showed no difference between there groups.The rate of postoperative nausea and vomiting(PONV) of group T and group M was higher than that of group TO,and there was no difference between group T and group M.The rate of postoperative pruritus and urine retention of group M was higher than that of the two other groups.【Conclusion】 Tramadol PCIA can provide the same analgesia effect as morphine in patients undergoing cesarean section and the rate of pruritus and urine retention was lower than that of morphine.Though the side effects such as nausea and vomiting were apparent,tramadol in combination with ondansetron can significantly reduce the incidence of side effects.