2002Zhongguo linchuang yaolixue yu zhiliaoxueRequires access

Evaluation of the efficacy of milrinone in treatment of chronic congestive heart failure

Li Ting

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Abstract

AIM: To estimate the efficacy of milrnone in treatment of congestive heart failure. METHODS: 122 cases of chronic congestive heart failure with different etiology were divided into milrinone group and dabutamine group randomly. Milrinone group accepted milrinone (10 mg·d -1 ) for 5 days, and dabutamine group accepted dabutamine (160 mg·d -1 ) for 5 days. The efficacy of treatments was evaluated. RESULTS: The effectiveness rates of cardiac function improvement were 93.9 % and 76.7 % in milrinone group and dabutamine group, respectively (P 0.05 ). The cardiac function improvement accompanied by the heart rate decrease and stable blood pressure in milrinone group. CONCLUSION: Milrinone is an effective drug for chronic congestive heart failure.

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What this paper is about

AIM: To estimate the efficacy of milrnone in treatment of congestive heart failure. METHODS: 122 cases of chronic congestive heart failure with different etiology were divided into milrinone group and dabutamine group randomly. Milrinone group accepted milrinone (10 mg·d -1 ) for 5 days, and dabutamine group accepted dabutamine (160 mg·d -1 ) for 5 days. The efficacy of treatments was evaluated. RESULTS: The effectiveness rates of cardiac function improvement were 93.9 % and 76.7 % in milrinone group and dabutamine group, respectively (P 0.05 ). The cardiac function improvement accompanied by the heart rate decrease and stable blood pressure in milrinone group. CONCLUSION: Milrinone is an effective drug for chronic congestive heart failure.

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Available abstract

AIM: To estimate the efficacy of milrnone in treatment of congestive heart failure. METHODS: 122 cases of chronic congestive heart failure with different etiology were divided into milrinone group and dabutamine group randomly. Milrinone group accepted milrinone (10 mg·d -1 ) for 5 days, and dabutamine group accepted dabutamine (160 mg·d -1 ) for 5 days. The efficacy of treatments was evaluated. RESULTS: The effectiveness rates of cardiac function improvement were 93.9 % and 76.7 % in milrinone group and dabutamine group, respectively (P 0.05 ). The cardiac function improvement accompanied by the heart rate decrease and stable blood pressure in milrinone group. CONCLUSION: Milrinone is an effective drug for chronic congestive heart failure.

Key concepts: Milrinone, Heart failure, Medicine, Cardiac function curve, Cardiology, Internal medicine, Anesthesia

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