Isolation and identification of chemical constituents in roots and rhizomes of Asarum heterotropoides Fr.Schmidt var. mandshuricum( Maxim. ) Kitag.
Qi We
Abstract
Qi We
Abstract
Objective To study the chemical constituents of in roots and rhizomes of Asarum heterotropoides Fr. Schmidt var. mandshuricum( Maxim.) Kitag.. Methods The compounds were isolated by chromatography on silica gel column and identified by the physiochemical properties and spectroscopic analysis. Results Sixteen compounds were obtained and identified as 1-O-p-coumaroyl-β-D-xylopyranosyl-(1→6)-β-D-glucopyraboside(1),1-O-feruloyl-β-D-xylopyranosyl-(1→6)-β-D-glucopyraboside(2),4,2',4',6'-tetrahydroxychalcone-2',4'-di-O-β-D-glucopyraboside(3),naringenin-7-O-β-D-glucopyranoside(4),8-desmethoxy-aristolactam-N-β-D-glucopyranoside(5),(R)-( +)-5-(2,3-dihydroxypropyl)-1,3-benzodioxole(6),3-methyl-6-hydroxy-8-methoxy-3,4-dihydroisocoumarin(7),( +)-7'-methoxylariciresinol(8),myristicin(9),safrole(10),(-)-asarinin(11),5,7-di-O-β-D-glucopy-ranosyl-2(S)-naringenin(12),methyleugenol(13),kakuol( 14),2-methoxyl-4,5-methylene-dioxypropiophenone( 15) and β-sitosterol( 16). Conclusions Compounds 6-8 are firstly isolated from Asarum genus. Compounds 3 and 5 are isolated from Asarum heterotropoides Fr. Schmidt var. mandshuricum(Maxim.)Kitag. for the first time.
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Objective To study the chemical constituents of in roots and rhizomes of Asarum heterotropoides Fr. Schmidt var. mandshuricum( Maxim.) Kitag.. Methods The compounds were isolated by chromatography on silica gel column and identified by the physiochemical properties and spectroscopic analysis. Results Sixteen compounds were obtained and identified as 1-O-p-coumaroyl-β-D-xylopyranosyl-(1→6)-β-D-glucopyraboside(1),1-O-feruloyl-β-D-xylopyranosyl-(1→6)-β-D-glucopyraboside(2),4,2',4',6'-tetrahydroxychalcone-2',4'-di-O-β-D-glucopyraboside(3),naringenin-7-O-β-D-glucopyranoside(4),8-desmethoxy-aristolactam-N-β-D-glucopyranoside(5),(R)-( +)-5-(2,3-dihydroxypropyl)-1,3-benzodioxole(6),3-methyl-6-hydroxy-8-methoxy-3,4-dihydroisocoumarin(7),( +)-7'-methoxylariciresinol(8),myristicin(9),safrole(10),(-)-asarinin(11),5,7-di-O-β-D-glucopy-ranosyl-2(S)-naringenin(12),methyleugenol(13),kakuol( 14),2-methoxyl-4,5-methylene-dioxypropiophenone( 15) and β-sitosterol( 16). Conclusions Compounds 6-8 are firstly isolated from Asarum genus. Compounds 3 and 5 are isolated from Asarum heterotropoides Fr. Schmidt var. mandshuricum(Maxim.)Kitag. for the first time.
Key concepts: Rhizome, Chemistry, Maxim, Traditional medicine, Stereochemistry, Medicine, Law, Political science