A comparative study of effectiveness and side effect risk on gerontalpatient wih dyslipidemia treated with rosuvastatin or simvastatin

Objective To investigate the effectiveness and safety of rosuvastatin or simvastatin on gerontalpatients with dyslipidemia.Methods A total of 86 cases with dyslipidemia during July 2009 to July 2012 were randomly divided into two groups:group A(Rosuvastatin) and group B(Simvastatin).Data were analyzed retrospectively to compare the effect and safety of rosuvastatin and simvastatin on gerontalpatients with dyslipidemia.Results The total efficiency of group A(97.67%) was higher than that of group B(79.07%),which had statistically significant difference(P0.05),According to the results,rosuvastin was better than simvastatin in the treatment of gerontal patients with dyslipidemia.There were no serious side effects during the treatment with rosuvastin or simvastatin,and datas such as routine blood test,examination of liver and renal function,blood creatine kinase and blood sugar pre and post treatment had no statistical significance.During the treatment there was 1 case of gastroenteric reaction in rosuvastin group,1 case of transaminase elevated slightly and 2 cases of astroenteric reaction in simvastatin group.Conclusion Rosuvastin and simvastatin were both safe and effective lipid-lowering drugs,but rosuvastin was more ideal than simvastatin in lipid-lowering effectiveness.