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2006•Zhonghua chuanranbing zazhiRequires access

Two AIDS patients associated with penicilliosis marniffei

Shen Bi

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Abstract

Objective The study was to investigate the clinical and histopathological features of pencillium marneffei infection in patients with AIDS.Methods Two cases of penicillium marneffei in fections of lymph node and intestinal mucosa were investigated morphologically by bematoxylin-eosin (HE),periodic acid-Schiff(PAS) and Gomori's methenamine silver(GMS) staining and the related literatures were reviewed.Results Small yeast-form fungi were detected in tissue sections by HE staining and sausage-like structures and septum formations were demonstrated clearly by PAS and GMS staining.Conclusions Penicillium marneffei infection can be diagnosed histopathologically if its characteristic structures are observed in tissue sections with positive PAS and GMS staining.

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What this paper is about

Objective The study was to investigate the clinical and histopathological features of pencillium marneffei infection in patients with AIDS.Methods Two cases of penicillium marneffei in fections of lymph node and intestinal mucosa were investigated morphologically by bematoxylin-eosin (HE),periodic acid-Schiff(PAS) and Gomori's methenamine silver(GMS) staining and the related literatures were reviewed.Results Small yeast-form fungi were detected in tissue sections by HE staining and sausage-like structures and septum formations were demonstrated clearly by PAS and GMS staining.Conclusions Penicillium marneffei infection can be diagnosed histopathologically if its characteristic structures are observed in tissue sections with positive PAS and GMS staining.

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Available abstract

Objective The study was to investigate the clinical and histopathological features of pencillium marneffei infection in patients with AIDS.Methods Two cases of penicillium marneffei in fections of lymph node and intestinal mucosa were investigated morphologically by bematoxylin-eosin (HE),periodic acid-Schiff(PAS) and Gomori's methenamine silver(GMS) staining and the related literatures were reviewed.Results Small yeast-form fungi were detected in tissue sections by HE staining and sausage-like structures and septum formations were demonstrated clearly by PAS and GMS staining.Conclusions Penicillium marneffei infection can be diagnosed histopathologically if its characteristic structures are observed in tissue sections with positive PAS and GMS staining.

Key concepts: Penicillium marneffei, Staining, Grocott's methenamine silver stain, Periodic acid–Schiff stain, Pathology, H&E stain, Lymph node, Microbiology

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