Vitamin B_6 ,654-2,Sodium Bicarbonate Respectively in the Comparison of Azithromycin in Gastrointestinal Reaction

Objective:To compare the vitamin B6 ,654-2,sodium bicarbonate in the azithromycin reaction of gastrointestinal tract effect. Method:Selected 150 cases whose respiratory tracted infection randomly from pediatric.And they were divided into group A,group B and group C, each group had 50 cases.On the basic treatment using azithromycin,supplemented with vitamin B6 ,654-2,sodium bicarbonate,in order to reduce gastrointestinal reaction,then compared the overall situation of gastrointestinal adverse reaction and occurrence degree of three groups after treatment using drug.Result:In nausea,vomiting,diarrhea and abdominal pain several adverse symptoms,group A was significantly lower than the group B, with significant difference(P 0.05),the difference between group B and group C was not significant(P 0.05);the occurrence of the adverse reactions, group A was significantly lower(P 0.05)than the B group,between group B and group C were not significant(P 0.05).Overall,the group A of adverse reaction incidence and degree of occurrence were relatively lower,with significant difference(P 0.05).Conclusion:In the azithromycin in gastrointestinal tract reaction,the overall effect of vitamin B6 with654-2 sodium bicarbonate and relatively better,more worthy of clinical application.