Study of sentinel lymph node in cervical cancer

Objective To investigate the influential factors of identifying sentinel lymph node (SLN)with methylene blue in cervical cancer,and evaluate the feasibility of SLN detection.Methods 40 cases with cervical cancer at stage ofⅠb-Ⅱb was injected 2-4 ml of methylene blue into cervix at 4-6 sites around the tumor about 90-180 min before operation.The blue-dyed lymph node(BDLN)was con- sidered as SLN.Tumor characteristic surgical findings,and specific locations of lymphatic dye uptake were re- corded and correlated with pathology results.Results Among 40 patients underwent this detection,and dye uptake was seen in 38 patients.Total number of SLNS was 67,23 SLNS indentified located in right pelvic and 44 SLNS located in left The SLNS were successfully detected in 28 patients(28/31).28 patients were diagnosed with lymph node metastases and 16 cases had both positive SLNS and pelvic lymph nodes,12 cases had positive SLNS only.The predictive rate was 90.32% and the false-negative rate was zero.Conclusion SLN detection undergoing hysterectomy is feasible and safe.