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2004•Journal of clinical surgeryRequires access

The application of fibrin sealant in the craniocerebral operation

Yong Wang

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Abstract

Objective To investigate the effective of fibrin sealant on brain tissue and the ability of hemostasis.Methods to compare the duration for hemostasis between the trial team(using fibrin sealant to hemostasis) and control team(without the helping of fibrin sealant,only using bipolar to coagulation);following CT scanning to approve the effect of fibrin sealant post-operation;HE staining to Investigate the effect on the neighbour brain tissue of fibrin sealant.Results With the help of fibrin sealant, abridging the time to hemostasis,the difference is significantly.The fibrin sealant were absorbable at short intervals.Conclusion It is credible and safe to apply the fibrin sealant in the craniocerebral operation.

About this research paper

What this paper is about

Objective To investigate the effective of fibrin sealant on brain tissue and the ability of hemostasis.Methods to compare the duration for hemostasis between the trial team(using fibrin sealant to hemostasis) and control team(without the helping of fibrin sealant,only using bipolar to coagulation);following CT scanning to approve the effect of fibrin sealant post-operation;HE staining to Investigate the effect on the neighbour brain tissue of fibrin sealant.Results With the help of fibrin sealant, abridging the time to hemostasis,the difference is significantly.The fibrin sealant were absorbable at short intervals.Conclusion It is credible and safe to apply the fibrin sealant in the craniocerebral operation.

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Available abstract

Objective To investigate the effective of fibrin sealant on brain tissue and the ability of hemostasis.Methods to compare the duration for hemostasis between the trial team(using fibrin sealant to hemostasis) and control team(without the helping of fibrin sealant,only using bipolar to coagulation);following CT scanning to approve the effect of fibrin sealant post-operation;HE staining to Investigate the effect on the neighbour brain tissue of fibrin sealant.Results With the help of fibrin sealant, abridging the time to hemostasis,the difference is significantly.The fibrin sealant were absorbable at short intervals.Conclusion It is credible and safe to apply the fibrin sealant in the craniocerebral operation.

Key concepts: Sealant, Fibrin, Hemostasis, Medicine, Fibrin Tissue Adhesive, Coagulation, Surgery, Chemistry

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