Clinical and Pathologic Study of Tubulointerstitial Lesions in IgA Nephropathy
Liu Guo
Abstract
Liu Guo
Abstract
Objective:To analyze the importance of tubulointerstitial lesions(TIL)in IgA Nephropathy(IgAN).Methods:The pathologic and clinical materials of 201 IgAN patients were analyzed.Results:The patients of TIL were about 86.1% in IgAN,these with mild TIL accounted for 47.3%,moderate TIL 21.9%,severe TIL was about 16.9% and these without TIL 13.9%.The relationship between TIL and the pathologic findingsis:with increase of the severity of TIL,the scores of vascular lesion,total glomerular lesion,hypercellularity and glomeruloselerosis increased gradually.Conclusion:With the increase of the severity of TIL,the condition of IgAN patients became worse.TIL may be one of the key factors for the prognosis of IgAN.
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Objective:To analyze the importance of tubulointerstitial lesions(TIL)in IgA Nephropathy(IgAN).Methods:The pathologic and clinical materials of 201 IgAN patients were analyzed.Results:The patients of TIL were about 86.1% in IgAN,these with mild TIL accounted for 47.3%,moderate TIL 21.9%,severe TIL was about 16.9% and these without TIL 13.9%.The relationship between TIL and the pathologic findingsis:with increase of the severity of TIL,the scores of vascular lesion,total glomerular lesion,hypercellularity and glomeruloselerosis increased gradually.Conclusion:With the increase of the severity of TIL,the condition of IgAN patients became worse.TIL may be one of the key factors for the prognosis of IgAN.
Key concepts: Medicine, Nephropathy, Lesion, Pathology, Gastroenterology, Endocrinology, Diabetes mellitus