2010•Medical Journal of West ChinaRequires access

Effects of Zhilonghuoxuetongyu capsule on cerebral ischemia-reperfusion injury rats

Luo Gang

Abstract

Objective To observe the protective effect of Zhilonghuoxuetongyu capsule(ZHTC) on cerebral ischemia-reperfusion injury in rats.Methods The model of focal cerebral ischemia-reperfusion in rats was made by middle cerebral artery occlusion.Rats of each group were feed with different dose ZHTC.The effect of ZHTC on the rats for behavioral state,morphology of brain tissue,and glial cell line-derived neurotrophic factor protein expression were observed.Results ZHTC can significant improve behavior after cerebral ischemia,reduce the degree of cerebral ischemia and the degree of cerebral ischemia and improve the lesions of brain tissue markedly.

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Key concepts: Medicine, Ischemia, Middle cerebral artery, Capsule, Anesthesia, Reperfusion injury, Neurotrophic factors, Occlusion