Antibiotic resistance study of Enterococcus faecium and Enterococcus faecalis

Objective:To investigate the anti-microbial resistance of Enterococcus faecium and Enterococcus faecalis to provide data for anti-infection therapy.Methods:We analyzed the clinical distribution and antibiotic resistance of E.faecium and E.faecalis which were collected from January 2005 to September 2009.Results:1286 isolates of E.faecium and 1042 isolates of E.faecalis were collected,and both of them mainly isolated from urine and sputamentum.Less than 5.0% of E.faecium and E.faecalis isolates were resistant to linezolid,vancomycin and teicoplanin,but more than 74.3% of them resistant to rifampicin.The resistance rate of E.faecium to ampicillin,penicillin and levofloxacin were higher than 92.3% and that of E.faecalis were lower than 22.5%.The resistant rate of E.faecium to gentamicin(high level)and nitrofurantoin was also higher than that of E.faecalis.Only the resistant rate to tetracycline was contrary.Conclusion:The resistance rate of E.faecium to most antibiotics is higher than that of E.faecalis.Vancomycin-resistant Enterococcus have been found,which should be paid close attention to.