Clinical Therapeutic Effect of Nasal/Facial Mask Bi-level Positive Airway Pressure Ventilation in Patients with Acute Pulmonary Edema

Objective To investigate the efficacy of nasal(facial)mask bi-level positive airway pressure(BiPAP)ventilation in patients with acute pulmonary edema. Methods Twenty-five patients with acute pulmonary edema either cardiogenic and non-cardiogenic were treated with nasal(facial) mask bi-level positive airway pressure(BiPAP)ventilation in addition to conventional treatment. Clinical symptoms, arterial blood gas(PaCO_2 PaO_2 and SaO_2), respiratory rate and heart rate, systolic and diastolic blood pressure were monitored to assess the efficacy of BiPAP mask ventilation. Results After applied BiPAP ventilation ,the clinical symptoms of all patients were improved significantly. In addition, clinical parameters showed significant improvement (P0.01) as compared with the same patients before received BiPAP mask ventilation. Conclusion Endotracheal intubation or tracheotomy could be avoided in patients with acute pulmonary edema by using the noninvasive BiPAP mask ventilation,BiPAP ventilation can evidently improve the symptoms and hypoxemia of the patient. BiPAP ventilation is safe and effective methods for salvaging acute pulmonany edema and can be extending its use in clinics.