Efficacy of gatifloxacin versus levofloxacin in the treatment of respiratory tract infections

Objective To evaluate the clinical efficacy and safety of gatifloxacin versus levofloxacin in treating respiratory tract bacterial infections Methods A randomized, double blind clinical design was used in 53 cases to accomplish the clinical trial, in which 26 patients were assigned to gatifloxacin group and 27 to levofloxacin group Results The rate of cure, efficacy, and bacterial eradication in the gatifloxacin group was 53 85%, 88 46%, and 90 91% in comparison with 40 74%, 62 96%, and 83.33% in the levofloxacin group ( P0.05 ) The rate of adverse reactions in gatifloxacin and levofloxacin groups was 11 54% and 14 81%,respectively ( P0.05 ) The side effects were mild Conclusion The efficacy and safety of gatifloxacin are comparable to levofloxacin Being a high efficient, broad spectrum, and safety antibacterial agent, Gatifloxacin can be used in the treatment of moderate or severe bacterial infections of the respiratory tract