Analysis on the clinical and pathological features of HBV-related glomerulonephritis

Aim: To analyze the clinical and pathological features of HBV-related glomerulonephritis and to provide foundation for its diagnosis and treatment. Methods: The clinical data, pathological and laboratory results of 53 glomerulonephritis patients with serum HBV marker positive were analyzed. Results: The incidence of HBV-related glomerulonephritis(positive group) was 43.4%. Among these patients, nephritic syndrome(60.87%) was the main manifestation, while membranous nephropathy(47.80%) and membranous proliferative glomerulonephritis(21.70%) were the principal pathological types. The creatinine clearance rate in positive group was lower than that of group in which HBV marker was negative (control group), while the output rate of urine protein was higher than that of control group(P0.05). Conclusion: There are differences in clinical manifestations, pathological types and laboratory results between positive group and control group. It is necessary to perform biopsy before determining treating regime for HBV-related glomerulonephritis.