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2002•Chinese Journal of New Drugs and Clinical RemediesRequires access

Celecoxib vs ibuprofen in treating osteoarthritis

MA Han-lin

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Abstract

AIM:To compare the therapeutic effects and safety of celecoxib and ibuprofen in treating osteoarthritis. METHODS: Sixty-six patients with osteoarthritis were divided into two groups.Celecoxib group of thirty-four patients received celecoxib 100 mg, po, bid, for 4 wk. Ibuprofen group of thirty-two patients received ibuprofen 300 mg, po, bid, for 4 wk. RESULTS: The total effective rates were 85 % in celecoxib group and 81 % in ibuprofen group(P 0.05). The adverse reaction rates were 18 % in celecoxib group and 34 % in ibuprofen group(P 0.05). CONCLUSION: Celecoxib is an effective and safe drug in treating osteoarthritis.

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AIM:To compare the therapeutic effects and safety of celecoxib and ibuprofen in treating osteoarthritis. METHODS: Sixty-six patients with osteoarthritis were divided into two groups.Celecoxib group of thirty-four patients received celecoxib 100 mg, po, bid, for 4 wk. Ibuprofen group of thirty-two patients received ibuprofen 300 mg, po, bid, for 4 wk. RESULTS: The total effective rates were 85 % in celecoxib group and 81 % in ibuprofen group(P 0.05). The adverse reaction rates were 18 % in celecoxib group and 34 % in ibuprofen group(P 0.05). CONCLUSION: Celecoxib is an effective and safe drug in treating osteoarthritis.

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Available abstract

AIM:To compare the therapeutic effects and safety of celecoxib and ibuprofen in treating osteoarthritis. METHODS: Sixty-six patients with osteoarthritis were divided into two groups.Celecoxib group of thirty-four patients received celecoxib 100 mg, po, bid, for 4 wk. Ibuprofen group of thirty-two patients received ibuprofen 300 mg, po, bid, for 4 wk. RESULTS: The total effective rates were 85 % in celecoxib group and 81 % in ibuprofen group(P 0.05). The adverse reaction rates were 18 % in celecoxib group and 34 % in ibuprofen group(P 0.05). CONCLUSION: Celecoxib is an effective and safe drug in treating osteoarthritis.

Key concepts: Celecoxib, Ibuprofen, Osteoarthritis, Medicine, Adverse effect, Internal medicine, Anesthesia, Pharmacology

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