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Analysis of 238 Cases of Adverse Drug Reaction in Our Hospital

Sheng Yao

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Abstract

OBJECTIVE:To explore the factors of adverse drug reaction(ADR)reported in our hospital in order to reduce the incidence of ADR induced by external factors and promote rational use of drugs.METHODS:238 cases of ADR reports collected by ADR Monitoring Center in our hospital from Jan.1st,2008 to Dec.25th,2009 were analyzed retrospectively.RESULTS:Of 238 ADR cases,59 cases occurred in senile patients over 60 years old(24.79%);230 ADR cases were resulted from intravenous administration(89.49%);161 ADR cases were mainly given antibiotics(62.65%).Main clinical manifestations in 167 cases were lesion of skin and its appendants(63.74%).15 ADR cases were caused by irrational use of drugs(6.30%).CONCLUSION:Great importance should be attached to ADR monitoring to promote rational use of drugs and reduce the incidence of ADR.

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OBJECTIVE:To explore the factors of adverse drug reaction(ADR)reported in our hospital in order to reduce the incidence of ADR induced by external factors and promote rational use of drugs.METHODS:238 cases of ADR reports collected by ADR Monitoring Center in our hospital from Jan.1st,2008 to Dec.25th,2009 were analyzed retrospectively.RESULTS:Of 238 ADR cases,59 cases occurred in senile patients over 60 years old(24.79%);230 ADR cases were resulted from intravenous administration(89.49%);161 ADR cases were mainly given antibiotics(62.65%).Main clinical manifestations in 167 cases were lesion of skin and its appendants(63.74%).15 ADR cases were caused by irrational use of drugs(6.30%).CONCLUSION:Great importance should be attached to ADR monitoring to promote rational use of drugs and reduce the incidence of ADR.

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Available abstract

OBJECTIVE:To explore the factors of adverse drug reaction(ADR)reported in our hospital in order to reduce the incidence of ADR induced by external factors and promote rational use of drugs.METHODS:238 cases of ADR reports collected by ADR Monitoring Center in our hospital from Jan.1st,2008 to Dec.25th,2009 were analyzed retrospectively.RESULTS:Of 238 ADR cases,59 cases occurred in senile patients over 60 years old(24.79%);230 ADR cases were resulted from intravenous administration(89.49%);161 ADR cases were mainly given antibiotics(62.65%).Main clinical manifestations in 167 cases were lesion of skin and its appendants(63.74%).15 ADR cases were caused by irrational use of drugs(6.30%).CONCLUSION:Great importance should be attached to ADR monitoring to promote rational use of drugs and reduce the incidence of ADR.

Key concepts: Medicine, Incidence (geometry), Adverse drug reaction, Drug reaction, Drug, Intravenous route, Internal medicine, Pharmacology

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