Assessment of globe and segmental heart function in children with single left ventricle by three dimensional echocardiography

Objective To explore the accuracy of three-dimensional echocardiography(3DE)for assessment of globe and segmental heart function in single left ventricle.Methods Seventy-two subjects were divided into two groups,36 healthy children and 36 patients with single left ventricle were enrolled in this study.There were no significant difference in age,sex,heart rate between the two groups.3DE data was acquired with the IE 33 system,and then analyzed by Q-lab software.End-diastolic volume(EDV),end-systolic volume(ESV)and eject fraction(EF)and volumes of each segment were acquired by 3DE.Results There were significant difference in EDV,ESV and EF between healthy volunteers and patients with single left ventricle(P0.05).The regional end-systolic of most segments except basal anteroseptal,basal inferoseptal and apex in patients with single left ventricle were significantly higher than those in the control group(P0.05).The regional end-diastolic of basal anterior,basal inferoseptal basal lateral,basal inferolateral,basal anterolateral,mid anteroseptal and mid inferior end-systolic volume were significantly higher than those in the control group(P0.05).Besides basal inferoseptal,the regional fraction(REF)of most segments in patients with single left ventricle decreased significantly compared with corresponding segments in the control group(P0.05).Conclusions Poorer globe and segmental ventricular function were found in patients with single left ventricle,and could be assessed accurately by 3DE.