Evaluation of left and right ventricular volume and systolic function in normal children with RT-3DE

Objective To evaluate the left and right ventricular volume and systolic function in normal children by fullvolume imaging of real-time three dimensional echocardiography(RT-3DE).Methods The full-volume imaging of left and right ventricle in 192normal children aged from 2months to 13years and 8months were obtained by RT-3DE.Totally 192 normal children were divided intoⅠ—Ⅴ groups by age.The left and right ventricular end-diastolic volume(EDV),endsystolic volume(ESV),stroke volume(SV),ejection fraction(EF),and the peak systolic volume-rate(PSVR) were analyzed with TomTec LV-analysis and RV-function.The above RT-3DE indexes between left and right ventricles were compared among the five age groups.Correlation analysis and curve estimation were performed on biventricular end-diastolic volume with age and physical development indexes.Results In each age group,there was no statistical difference of biventricular EDV,while for ESV,SV,PSVR,no significant difference was found in some groups(all P0.05).Left ventricle EF was higher than right ventricle EF(P0.05).EDV of left and right ventricle had good positive correlation with age,height,weight and body surface area(BSA,r0.85,P0.001).Curve estimation demonstrated that the interrelation between biventricular EDV and age,height,weight,BSA could be best expressed by power model,the best matched model was found with BSA.The regression equation was left ventricle EDV=38.58BSA 1.41(r 2 =0.89,P0.001),right ventricle EDV=37.46BSA 1.29(r 2 =0.85,P0.001).Conclusion The biventricular volumes attained with RT-3DE are similar with each other.There is balance between left and right ventricle pumping function.The ventricular volume increases with age in an exponential mode.