Clinical Application of ERCP in Postoperative Pancreatitis Prevention for High-Risk Patients after Endoscopic Duct Stents

Objective To explore the clinical application in the prevention of post-ERCP pancreatitis(PEP) for high-risk patients undergoing endoscopic duct stent placement.Methods The clinical data of 112 patients with high-risk PEP between January 2005 and June 2010 in this hospital were analyzed retrospectively.According to stents placement or not,112 patients were divided into stent placement group(n=52) treated by ERCP and stents placement and non-stent placement group(n=60) treated by ERCP without stent retaining.PEP was diagnosed according to Cotton standard,the incidence rate of PEP was compared between two groups and the high-risk influencing factors were analyzed.Results According to Cotton standard,there were only 3 patients(5.8%) diagnosed PEP in the stent placement group,all symptoms disappeared on 48 h after operation,without a diagnosis for severe acute pancreatitis.There were 9 patients(15.0%) diagnosed PEP in the non-stent placement group,and 2 patients were severe acute pancreatitis,The status was better undergoing fasting,aprotinin,anti-inflammatory,and enteral nutrition supporting treatment.The incidence of PEP was associated with younger women(age ≤45 years),Oddi sphincter dysfunction,and no dilation of bile duct(P0.05).Conclusion It can obviously reduce PEP occurrence in high-risk patients with stent placement.