Changes in hemodynamics in end stage liver failure patients after liver transplantation

Objective:To investigate the changes in hemodynamics in end stage liver failure patients after liver transplantation.Methods:Five patients with liver transplantation were included in this study.SwanGanz catheters were inserted and central venous pressure (CVP),mean pulmonary arterial pressure (MPAP), pulmonary capillary wedge pressure (PCWP),cardiac output (CO),mean arterial pressure (MAP),systemic vascular resistance index (SVRI),pulmonary vascular resistance index (PVRI),heart rate (HR) were measured from 1 to 3 days after the operation.Results:MAP,PCWP,and CVP decreased and HR increased after the admission to ICU,and then they were increased within 3 days.Cardiac index(CI) showed no marked changes within 3 days.SVRI and PVRI were decreased at the admission,and then were improved in the next 3 days.Conclusions:In end stage liver failure patients with liver transplantation,the hemodynamics is unstable,indicating hypovolemia.It is necessary to calculate the volume deficit and determine the resuscitation volume.