2014•PubMedRequires access

[Progress of CD8+ T cell-mediated immune response to Toxoplasma gondii infection].

Bin Wu, Fang-Li Lyu

Abstract

Toxoplasma gondii is an obligate intracellular protozoan parasite, which infects warm-blooded animals including humans. T. gondii infection in the immune-competent individual is largely asymptomatic, but it can cause severe toxoplasmosis in immune-deficiency patients. T cell-mediated immunity plays an important role in resistance against T. gondii. Therefore, this review focuses on the progress of CD8+ T cell-mediated immune response to T. gondii infection.

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Key concepts: Toxoplasma gondii, Immune system, Toxoplasmosis, Biology, Intracellular parasite, Protozoan parasite, Immunology, Obligate