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Study of serum intercellular adhesion molecule-1,vascular adhesion Molecule-1,and P-selectin in patients with coronary heart disease

Lixia Xu

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Abstract

Objective:To explore the changes of serum intercellular adhesion molecule-1(sICAM- 1),vascular adhesion molecule-1(sVCAM-1),and P-selectin level in patients with coronary heart disease.Methods:A total of 85 patients with coronary heart disease,including 30 cases of SAP, 30cases of UA,and 25 cases of AMI,were subjected to detect the serum levels of sICAM-1,sV- CAM-l,and P-selectin using ELISA method.Fifty normal individuals was used as control.Re- sults:Compared with those of control,the serum levels of the four indexes mentioned above of AMI,UA,and SAP groups(P0.01)were higher.Conclusion:The four indexes mentioned above may involve in the pathogenesis and process of coronary heart disease,and might be an available index that reflexes the sevenity of coronary heart disease.

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What this paper is about

Objective:To explore the changes of serum intercellular adhesion molecule-1(sICAM- 1),vascular adhesion molecule-1(sVCAM-1),and P-selectin level in patients with coronary heart disease.Methods:A total of 85 patients with coronary heart disease,including 30 cases of SAP, 30cases of UA,and 25 cases of AMI,were subjected to detect the serum levels of sICAM-1,sV- CAM-l,and P-selectin using ELISA method.Fifty normal individuals was used as control.Re- sults:Compared with those of control,the serum levels of the four indexes mentioned above of AMI,UA,and SAP groups(P0.01)were higher.Conclusion:The four indexes mentioned above may involve in the pathogenesis and process of coronary heart disease,and might be an available index that reflexes the sevenity of coronary heart disease.

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Available abstract

Objective:To explore the changes of serum intercellular adhesion molecule-1(sICAM- 1),vascular adhesion molecule-1(sVCAM-1),and P-selectin level in patients with coronary heart disease.Methods:A total of 85 patients with coronary heart disease,including 30 cases of SAP, 30cases of UA,and 25 cases of AMI,were subjected to detect the serum levels of sICAM-1,sV- CAM-l,and P-selectin using ELISA method.Fifty normal individuals was used as control.Re- sults:Compared with those of control,the serum levels of the four indexes mentioned above of AMI,UA,and SAP groups(P0.01)were higher.Conclusion:The four indexes mentioned above may involve in the pathogenesis and process of coronary heart disease,and might be an available index that reflexes the sevenity of coronary heart disease.

Key concepts: Pathogenesis, Medicine, Coronary heart disease, Cell adhesion molecule, Internal medicine, Adhesion, Cardiology, Intercellular Adhesion Molecule-1

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Study of serum intercellular adhesion molecule-1,vascular adhesion Molecule-1,and P-selectin in patients with coronary heart disease — Research Paper | ScholarLens