Comparison between Remifentanil,Propofol total intravenous anesthesia and inhalation combined anesthesia in laparoscopic cholecystectomy

Objective To compare the clinical curative effects of Propofol,Remifentanil total intravenous anesthesia and inhalation in laparoscopic cholecystectomy(LC).Methods Sixty-eight patients who were going to receive LC surgery were randomly divided into the control group in which the patients would receive inhalation combined anesthesia and the observation group in which the patients would receive total intravenous anesthesia.The patients in the control group received the endotracheal intubation after the induction by Propofol,Fentanyl,Succinylcholine chloride and were maintained with Isoflurane anesthesia during operation while the patients in the observation group were induced with Remifentanil instead of Fentanyl and Maintained with Remifentanil and Nepal Propofol.The rest medication was equivalent to the patients in the control group.The blood pressure,heart rate recovery time,postoperative spontaneous breathing,eye opening time and extubation time of all the patients after induction,intubation and incision were compared.Results The heart rate of the patients in the observation group after induction was lower than that of the patients in the control group,while postoperative heart rate was higher than that of the patients in the control group,systolic blood pressure after induction and intubation was lower than that of the patients in the control group (P0.01).Heart rate and blood pressure of the patients in both groups had no statistical differences(P0.05).The spontaneous breathing recovery time,eye opening time and extubation time of the patients in the observation group were significantly shorter than those of the patients in the control group(P0.05).Conclusion Compared with inhalation combined anesthesia,Propofol,Remifentanil total intravenous anesthesia in LC which is a safe and effective anesthesia method can induce more smoothly and make postoperative patients wake up more quickly.