The Detection and Analysis about Antibiotic Resistance of Producing ESBLs Escherichia Coli and Klebsiella Pneumoniae in Urine Culture

Objective:To determine the prevalence of strains producing ESBLs among Klebsiella pneumoniae and Escherichia coli, and investigate the antibiotic resistance of these strains. Methods:Producing ESBLs bacteria were detected using Vitek-32 system. Results: Among 87 strains of Escherichia coli, 63 strains of Klebsiella Pneumoniase. producing ESBLs bacteria accounted for 44.8%, 39.7%. The resistance rate of ESBLs-producing strains to ceftazidime, cefotaxime was 96.9%～97.2%, 94.9% higher than that of non-ESBLs-producing strains. ESBLs-producing strains had higher resistance rate to aminoglycosides, quinolones, sulfonamides (80.5%?91.6%?92.5% respectively). All tested strains However, were susceptible to imipenem. Conclusion:To deal with the ESBLs-producing strains, such antibiotics as imipenem,β-lactamase inhibitor combinations and others which are sensentive to such strains can be used.