Stroke Volume Variation in the Evaluation of Fluid Responsiveness in Septic Shock Patients

Objective: To evaluate fluid responsiveness by stroke volume variation(SVV) in patients with septic shock.Methods: 16 septic shock patients were enrolled in the study.According to the responsiveness of fluid loading,the patients were divided into responsive group(n=12) and nonresponsive group(n=4).The SVV values of two groups were retrospectively analyzed.The receiver operating characteristic curve was drafted to determine the cut-off value of SVV for predicting fluid responsiveness.Results: Among the 16 septic shock patients,12 were responsive to fluid loading,4 were not;before the fluid loading,central venous pressure,heart rate and mean arterial pressure in both groups showed no significant difference whereas SVV in the responsive group was much higher than that in the nonresponsive group(P0.01).Using the threshold of SVV≥12.5% to predict fluid responsiveness,the sensitivity was 80%,specificity was 100%.Conclusion: SVV accurately predict fluid responsiveness in septic shock patients.