The Clinical Analysis of 279 Cases with Premature Rupture of Membrane

Objective To investigate the reasons of premature rupture of membrane(PROM)and its association with delivery option and neonatal outcome.Methods Medical records of 279 pregnant women with PROM were reviewed retrospectively.The delivery option and neonatal outcome were analyzed and compared between the women with delivery less than 24 hours and more than 24 hours after PROM with different gestation weeks,and between women with and without PROM.Results High frequency pregnancy had the highest PROM prevalence of 39.42%,which was followed by fetal-pelvic disproportion,vaginitis,malpresentation and multiple pregnancy.Among 222 women with delivery less than 24 hours after PROM,there were 81.08% vaginary deliveries and 18.92% by cesarean sections.Asphyxia neonatorum occurred in 7 infants and one had neonatal infection.While among 57 women with delivery more than 24 hours after PROM,there were 77.19% vaginary deliveries and 22.81% cesarean sections,and 17.86% infants with asphyxia neonatorum and 7 infants with infection.There was no significant difference in delivery option while significant difference existed in asphyxia neontorum and infection rate.There were 28 premature infants,5 infants with asphyxia neonatorum,4 with infection,2 with intractanial hemorrhage,2 with idiopathic respiratory distress syndrome(IRDS)and 2 with perinatal deaths.Among 251 term infants,8 had asphyxia neonatorum and 4 had infection,No IRDS and intractanial hemorrhageand occurred.There was significant difference in the rate of asphyxia neonatorum,infection,intractanial hemorrhage and IRDS.The CS rate of PROM group was 20.43%,which was significantly lower than that of normal pregnancy women(54.03%).Conclusion If the origin of premature rupture of membrane should be monitored and managed as early as possible,conducte dystocia rate may be controlled so that the morbidity of pregnany women and infants can be lowered.Vaginal delivery should also be advocated for PROM women because PROM is not the direct reason of dystocia.