Impact of percutaneous coronary intervention performed during recovery phase on left ventricular remodeling in acute myocardial infarction patients

Objective To assess the impact of percutaneous coronary intervention(PCI) performed during recovery phase on left ventricular(LV) remodeling in acute myocardial infarction(AMI) patients.Methods Twenty-eight patients(group Ⅰ) with first-time MI and having received successful PCI during recovery phase were prospectively studied;22 patients(group Ⅱ) with first-time AMI but without receiving PCI were enrolled as control.In both groups,serial echocardiographic examinations were performed before PCI [(4.5±3.3) days] and during follow up [(6.9±1.3) months after PCI] to assess the changes in LV volumes,systolic and diastolic function. Results In group Ⅰ,LV volume was decreased and systolic function was improved after PCI during follow-up,but LV diastolic function remained unchanged.LV volume was smaller and systolic and diastolic function was better in group Ⅰ than in group Ⅱ(all P0.05). Conclusions PCI performed during the recovery phase of acute myocardial infarction may significantly improve the heart function.