Effect of radical mastectomy and extended radical mastectomy on stage II,III breast cancer:a report of 691 cases

Objective To explore the therapeutic effects of radical mastectomy(RM) and extended radical mastectomy(ERM) for stage II, III breast cancer. Methods The 5 year and 10 year survival rates in 691 patients with stage II, III breast cancer treated either by extended radical mastectomy or radical mastectomy were retrospectively analyzed . Out of the 691 patients, 206 stage II cases and 193 stage III cases underwent RM, and 142 stage II and 150 stage III cases received ERM. Results In patients with stage II, III breast cancer located in the central portion or medial portion of mammary, the 5 year survival rates and in stage III patients 10 year survival rate after ERM were significantly higher than those after RM (P0.01). The 10 year survival rate in patients with stage II, III breast cancer located in the upper lateral quadrant , and the 5 year survivol in stage III patients after ERM were significantly than those after RM (P0.05). Conclusions The results suggest that ERM should be considered for patients with stage II, III breast cancer located in the central part and medial area of mammary , and stage III breast cancer located in the upper lateral quadrant of mammary.