The Effects of Electroacupuncture on Myocardial Ischemia-reperfusion Arrhythmia in Rabbits
You Xing-hong
Abstract
You Xing-hong
Abstract
Objective:To observe the effects of electroacupuncture on myocardial ischemia-reperfusion arrhythmia in rabbits,and its mechanism.Methods:18 rabbits were randomly divided into 3 groups,namely sham operation group(S group),ischemia-reperfusion group(IR group),electroacupuncture group(EA group).Myocardial ischemia-reperfusion preparation model was induced by ligation of the left anterior descending coronary artery 30min and 60min reperfusion.All the indexes(reperfusion arrhythmia,left ventricular function and serum NO) were measured.Results:Compared with IR group,the incidence of reperfusion arrhythmias of EA group was progressively decreased(P0.05).left ventricular pressure and maximum rate of rise and fall of left ventricular systolic pressure was higher than IR group(P0.01,P0.05),serum NO were significantly increased(P0.01).Conclusion:Electroacupuncture has a protective effect on myocardial ischemia-reperfusion arrhythmia,the mechanism may be related to increasing NO content.
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Objective:To observe the effects of electroacupuncture on myocardial ischemia-reperfusion arrhythmia in rabbits,and its mechanism.Methods:18 rabbits were randomly divided into 3 groups,namely sham operation group(S group),ischemia-reperfusion group(IR group),electroacupuncture group(EA group).Myocardial ischemia-reperfusion preparation model was induced by ligation of the left anterior descending coronary artery 30min and 60min reperfusion.All the indexes(reperfusion arrhythmia,left ventricular function and serum NO) were measured.Results:Compared with IR group,the incidence of reperfusion arrhythmias of EA group was progressively decreased(P0.05).left ventricular pressure and maximum rate of rise and fall of left ventricular systolic pressure was higher than IR group(P0.01,P0.05),serum NO were significantly increased(P0.01).Conclusion:Electroacupuncture has a protective effect on myocardial ischemia-reperfusion arrhythmia,the mechanism may be related to increasing NO content.
Key concepts: Electroacupuncture, Medicine, Cardiology, Internal medicine, Ischemia, Myocardial ischemia, Anesthesia, Ligation