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Study on apoptosis of lung carcinoma cells induced by retionoic acid

Wen Zhong

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Abstract

[ Objective ] To study apoptosis of lung carcinoma cells induced by retionoic acid (RA) . [ Method ] Apoptosis induced by RA in A59 cell lines of lung cancer was detected with acredine organge (AO) fluororent staining and trans ecetron microscope respectively. [Result]After 6 days RA and A59 cell lines were mixed with 5 % C02 incubator, cells were reduced from 20 000/L to 9 000/L, and apoptosis cells and indexes in RA groups were higher than those of control group, P 0.05. Apoptosis cells or bodies in RA groups were also seen with TEM. [ Conclusion] RA can inhibit the increase and induce the apoptosis of lung carcinoma cells.

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What this paper is about

[ Objective ] To study apoptosis of lung carcinoma cells induced by retionoic acid (RA) . [ Method ] Apoptosis induced by RA in A59 cell lines of lung cancer was detected with acredine organge (AO) fluororent staining and trans ecetron microscope respectively. [Result]After 6 days RA and A59 cell lines were mixed with 5 % C02 incubator, cells were reduced from 20 000/L to 9 000/L, and apoptosis cells and indexes in RA groups were higher than those of control group, P 0.05. Apoptosis cells or bodies in RA groups were also seen with TEM. [ Conclusion] RA can inhibit the increase and induce the apoptosis of lung carcinoma cells.

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Available abstract

[ Objective ] To study apoptosis of lung carcinoma cells induced by retionoic acid (RA) . [ Method ] Apoptosis induced by RA in A59 cell lines of lung cancer was detected with acredine organge (AO) fluororent staining and trans ecetron microscope respectively. [Result]After 6 days RA and A59 cell lines were mixed with 5 % C02 incubator, cells were reduced from 20 000/L to 9 000/L, and apoptosis cells and indexes in RA groups were higher than those of control group, P 0.05. Apoptosis cells or bodies in RA groups were also seen with TEM. [ Conclusion] RA can inhibit the increase and induce the apoptosis of lung carcinoma cells.

Key concepts: Apoptosis, Staining, Carcinoma, Lung, Carcinoma Cell, Chemistry, Cell culture, Lung cancer

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