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2006•Zhongguo fuyou baojianRequires access

Clinical observation of dexamethasone used in treatment of infective brain edema

Mai Shui

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Abstract

Objective:To probe into the effective therapy of treating infective brain edema.Methods:87 cases of infective brain edema were divided into two groups, 44 cases of treatment group were treated with dexamethasone and mannitol, 43 cases of control group were treated with lasix and mannitol.The levels of TNF-α, IL-1, NO of CSF were determined in two group by ELISA method and Griess method to compare the curative effect, mortality and sequelae rate in two groups.Results:①The levels of TNF-α, IL-1, NO of treatment group were significantly lower than those of control group (P0.05);②The curative effect of treatment group was significantly better than that of control group (P0.05);③The mortality and sequelae rate of treatment group were significantly lower than that of control group (P0.05).Conclusion:Dexamethasone was effective drug of infective brain edema of choice, and dexamethasone united mannitol could be regimen of choice.

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What this paper is about

Objective:To probe into the effective therapy of treating infective brain edema.Methods:87 cases of infective brain edema were divided into two groups, 44 cases of treatment group were treated with dexamethasone and mannitol, 43 cases of control group were treated with lasix and mannitol.The levels of TNF-α, IL-1, NO of CSF were determined in two group by ELISA method and Griess method to compare the curative effect, mortality and sequelae rate in two groups.Results:①The levels of TNF-α, IL-1, NO of treatment group were significantly lower than those of control group (P0.05);②The curative effect of treatment group was significantly better than that of control group (P0.05);③The mortality and sequelae rate of treatment group were significantly lower than that of control group (P0.05).Conclusion:Dexamethasone was effective drug of infective brain edema of choice, and dexamethasone united mannitol could be regimen of choice.

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Available abstract

Objective:To probe into the effective therapy of treating infective brain edema.Methods:87 cases of infective brain edema were divided into two groups, 44 cases of treatment group were treated with dexamethasone and mannitol, 43 cases of control group were treated with lasix and mannitol.The levels of TNF-α, IL-1, NO of CSF were determined in two group by ELISA method and Griess method to compare the curative effect, mortality and sequelae rate in two groups.Results:①The levels of TNF-α, IL-1, NO of treatment group were significantly lower than those of control group (P0.05);②The curative effect of treatment group was significantly better than that of control group (P0.05);③The mortality and sequelae rate of treatment group were significantly lower than that of control group (P0.05).Conclusion:Dexamethasone was effective drug of infective brain edema of choice, and dexamethasone united mannitol could be regimen of choice.

Key concepts: Medicine, Dexamethasone, Mannitol, Edema, Brain edema, Regimen, Anesthesia, Cerebral edema

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