An Investigation of Serum Allergen-specific IgE Antibody of 1844 Patients with Allergic Dermatosis

Objective To investigate the allergen-specific IgE antibody and total serum immunoglobulin E(IgE) levels in patients with common allergic dermatosis. Methods The specific allergen and total serum IgE level in 1844 cases with allergic dermatosis were detected with enzyme immunoassay method.Including 884 cases with urticaria,704 cases with eczema,256 cases with atopic dermatitis.Results Among 1844 cases with allergic dermatosis,total serum IgE level of 1148 cases(62.3%) were positive(≥90IU/mL).In food group,the most common allergen was shrimp/crab mix(24.1%),fish(19.0%) was the next,then were beef/mutton mix(13.7%),milk(11.3%),eggs(8.6%) and soybeen/peanut mix(4.0%);in inhalation group,the most common allergen was the dust mite(30.5%),then was polyvalent fungus(29.8%),artemisia(24.8%),dermatophagoides pteronyssinus(24.2%),tree pollen(23.5%), and ragweed(9.7%).Conclusion Enzyme immunoassay method could help us to find relevant allergens and to confirm allergic constitution of patients,and could provide foundation of the prevention and treatment of allergic dermatosis.