The correlation study of MR susceptibility and perihematomal brain edema in cerebral hemorrhage

Objective:To investigate the relationship between MR susceptibility and perihematomal brain edema(PHBE)in cerebral hemorrhage.Methods:Fifty-two patients who had intracerebral hemorrhage in parenchyma were selected.MRI and quantitative susceptibility mapping(QSM)scan were performed on the 3rd and 10 th day after onset.The MR susceptibility of hemorrhage was calculated in QSM,and PHBE was measured in T2-FLAIR imaging.Pearson statistical method was used to analyze the relationship between MR susceptibility and PHBE.Results:The average MR susceptibility of hemorrhage was(4794.6±420.4)ppm and PHBE was(7.49±3.12)mL on the third day.The correlation between them was significant(r=0.974,P0.001).On the 10 th day,the average MR susceptibility was(7388.6±3589.2)ppm and PHBE was(11.23±3.79)mL.The correlation was significant(r=0.901,P0.001).Conclusion:The release of iron ions from the blood after being dissolved is likely to be an important part in the formation of PHBE.From this point,MR susceptibility measurement of iron content in hematoma is of help is observing PHBE process.