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Application of pulse indicator continuous cardiac output monitor in the fluid resuscitation therapy in elderly patients with septic shock

Haixia Wang

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Abstract

Objective To investigate the guiding significance of pulse indicator continuous cardiac output(PICCO) for the fluid resuscitation in elderly patients with septic shock.Methods Twenty-four elderly patients with septic shock were divided into observation group and control group,twelve cases in each group.The patients in observation group were treated with fluid resuscitation under the guidance of PICCO monitor,while the patients in control group were treated with fluid resuscitation under the guidance of monitoring central venous pressure,then the curative effect was compared between the two groups.Results On the first day of treatment,there was no statistical difference in the blood cell and neutrophil counts,mixed venous oxygen saturation(SvO2),the levels of procalcitonin(PCT) and lactic acid(LA) between the two groups(P0.05).On the second and third days of treatment,the white blood cell,neutrophil counts and the levels of LA and PCT in observation group were significantly lower than those in control group(P0.05),but SvO2 was significantly higher(P0.05).Compared with control group,the mechanical ventilation time was significantly shorter(P0.05),and the case fatality within 28 days was lower in observation group(P0.05).Conclusion PICCO monitor has important guiding significance in the treatment of fluid resuscitation in elderly patients with septic shock,which can significantly improve blood gas analysis index,shorten the mechanical ventilation time and reduce mortality.

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What this paper is about

Objective To investigate the guiding significance of pulse indicator continuous cardiac output(PICCO) for the fluid resuscitation in elderly patients with septic shock.Methods Twenty-four elderly patients with septic shock were divided into observation group and control group,twelve cases in each group.The patients in observation group were treated with fluid resuscitation under the guidance of PICCO monitor,while the patients in control group were treated with fluid resuscitation under the guidance of monitoring central venous pressure,then the curative effect was compared between the two groups.Results On the first day of treatment,there was no statistical difference in the blood cell and neutrophil counts,mixed venous oxygen saturation(SvO2),the levels of procalcitonin(PCT) and lactic acid(LA) between the two groups(P0.05).On the second and third days of treatment,the white blood cell,neutrophil counts and the levels of LA and PCT in observation group were significantly lower than those in control group(P0.05),but SvO2 was significantly higher(P0.05).Compared with control group,the mechanical ventilation time was significantly shorter(P0.05),and the case fatality within 28 days was lower in observation group(P0.05).Conclusion PICCO monitor has important guiding significance in the treatment of fluid resuscitation in elderly patients with septic shock,which can significantly improve blood gas analysis index,shorten the mechanical ventilation time and reduce mortality.

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Available abstract

Objective To investigate the guiding significance of pulse indicator continuous cardiac output(PICCO) for the fluid resuscitation in elderly patients with septic shock.Methods Twenty-four elderly patients with septic shock were divided into observation group and control group,twelve cases in each group.The patients in observation group were treated with fluid resuscitation under the guidance of PICCO monitor,while the patients in control group were treated with fluid resuscitation under the guidance of monitoring central venous pressure,then the curative effect was compared between the two groups.Results On the first day of treatment,there was no statistical difference in the blood cell and neutrophil counts,mixed venous oxygen saturation(SvO2),the levels of procalcitonin(PCT) and lactic acid(LA) between the two groups(P0.05).On the second and third days of treatment,the white blood cell,neutrophil counts and the levels of LA and PCT in observation group were significantly lower than those in control group(P0.05),but SvO2 was significantly higher(P0.05).Compared with control group,the mechanical ventilation time was significantly shorter(P0.05),and the case fatality within 28 days was lower in observation group(P0.05).Conclusion PICCO monitor has important guiding significance in the treatment of fluid resuscitation in elderly patients with septic shock,which can significantly improve blood gas analysis index,shorten the mechanical ventilation time and reduce mortality.

Key concepts: Medicine, Procalcitonin, Resuscitation, Septic shock, Anesthesia, Sepsis, Mechanical ventilation, Cardiac index

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Application of pulse indicator continuous cardiac output monitor in the fluid resuscitation therapy in elderly patients with septic shock — Research Paper | ScholarLens