2007•Journal of Medical Science Yanbian UniversityRequires access

Effects of the compounds Yuanguizhi on SOD and MDA in serum of the acute liver injury

Cui Jing-ai

Abstract

OBJECTIVE To observe the effects of the compounds Yuanguizhi on superoxide dismutase(SOD) and malondialdehyde(MDA) in serum of the acute liver injury induced by carbon tetrachloride(CCl4).METHODS The acute liver injury model of rats was induced by CCl4. The activity of SOD and content of MDA in serum were measured by colorimetric method after treatment.RESULTS The activities of SOD in the compounds Yuanguizhi group were significantly higher and the content of MDA in the compounds Yuanguizhi group were obviously lower than model group in serum of the acute liver injury induced by CCl4.CONCLUSION The compounds Yuanguizhi could clear the free radicals and has the effect of anti-lipid peroxidation.

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Key concepts: Malondialdehyde, Carbon tetrachloride, Superoxide dismutase, Lipid peroxidation, CCL4, Chemistry, Liver injury, Radical