Clinical observation of tiotropium treatment for COPD patients

Objective To investigate the clinical efficacy of tiotropium inhaler in elderly smokers with stable chronic obstructive pulmonary disease(COPD).Methods 90 elderly smokers with stable COPD were evenly and randomly divided into two groups,and their clinical data were reviewed.The treatment group were given inhaled tiotropium 18 micrograms and albuterol aerosol once a day,and the control group were treated with 0.1 g aminophylline and albuterol aerosol orally every 12 hours.All the patients were followed up for 2 months to observe their improvement.Results In the treatment group,their St George score decreased significantly compared with the control group,and the scores of FEV1/Pred,FEV1,and FEV1/FVC increased obviously(P0.01).However,the control group showed no significant difference(P0.05).Conclusion Inhaled tiotropium and salbutamol aerosol can significantly improve lung function and life quality of elderly smokers with stable COPD.