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Application Evaluation of Immunoturbidimetric Method for β_2-microglobulin on Roche Automatic Biochemical Analyzer

XI Jin-ou

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Abstract

Objective To evaluate the analysis capability of β2-microglobulin by Roche automatic biochemical analyzer with immunoturbidimetric method.Methods The sensitivity,precision and jamming test were used to evaluate immunoturbidimetric method for β2-microglobulin on Roche automatic biochemical analyzer.Results The mean CV for within-run assay was 1.74%,CV for between-run assay was 2.79%,and the average recovery was 99%.Low concentration of Hb(2 g/L) and TG( 4.5 mmol/L) didn't interfere with the detection results.Immunoturbidimetric method on Roche and Hitachi 7170 automatic biochemical analyzer showed good concordance in detection of β2-microglobulin(Y=0.904X+0.18,γ=0.923,P0.01).Conclusion Immunoturbidimetric method has a high sensitivity and precision which is suitable for automatic biochemical analyzer in routine laboratory.

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Objective To evaluate the analysis capability of β2-microglobulin by Roche automatic biochemical analyzer with immunoturbidimetric method.Methods The sensitivity,precision and jamming test were used to evaluate immunoturbidimetric method for β2-microglobulin on Roche automatic biochemical analyzer.Results The mean CV for within-run assay was 1.74%,CV for between-run assay was 2.79%,and the average recovery was 99%.Low concentration of Hb(2 g/L) and TG( 4.5 mmol/L) didn't interfere with the detection results.Immunoturbidimetric method on Roche and Hitachi 7170 automatic biochemical analyzer showed good concordance in detection of β2-microglobulin(Y=0.904X+0.18,γ=0.923,P0.01).Conclusion Immunoturbidimetric method has a high sensitivity and precision which is suitable for automatic biochemical analyzer in routine laboratory.

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Available abstract

Objective To evaluate the analysis capability of β2-microglobulin by Roche automatic biochemical analyzer with immunoturbidimetric method.Methods The sensitivity,precision and jamming test were used to evaluate immunoturbidimetric method for β2-microglobulin on Roche automatic biochemical analyzer.Results The mean CV for within-run assay was 1.74%,CV for between-run assay was 2.79%,and the average recovery was 99%.Low concentration of Hb(2 g/L) and TG( 4.5 mmol/L) didn't interfere with the detection results.Immunoturbidimetric method on Roche and Hitachi 7170 automatic biochemical analyzer showed good concordance in detection of β2-microglobulin(Y=0.904X+0.18,γ=0.923,P0.01).Conclusion Immunoturbidimetric method has a high sensitivity and precision which is suitable for automatic biochemical analyzer in routine laboratory.

Key concepts: Spectrum analyzer, Beta-2 microglobulin, Chromatography, Fully automatic, Chemistry, Medicine, Computer science, Engineering

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Application Evaluation of Immunoturbidimetric Method for β_2-microglobulin on Roche Automatic Biochemical Analyzer — Research Paper | ScholarLens