Study on the Antibacterial Activity of Lycium Barbarum Polysaccharide and Astragalus Polysaccharide

Objective: To explore the antibacterial activity of Lycium barbarum polysaccharide and Astragalus polysaccharide,and to determine whether the pH values affect this antibacterial activity.Methods: The inhibitory effects of Lycium barbarum polysaccharide and Astragalus polysaccharide on bacteria and mycete were determined by K-B method under different pH value.Results: As for bacteria,the inhibition of 8 mg/mL Lycium barbarum polysaccharide was the best,and the inhibition of 0.02 mg/mL Astragalus polysaccharide was the best.As for mycete,the inhibition of Lycium barbarum polysaccharide strengthened as its concentration increased,while the inhibition of Astragalus polysaccharide reached best at the concentration of 0.02 mg/mL.Both Lycium barbarum polysaccharide and Astragalus polysaccharide with pH 6 showed the best inhibitory effects.Conclusion: Lycium barbarum polysaccharide and Astragalus polysaccharide had inhibitory effects on bacteria and mycete to a certain extent and their antibacterial activity were influenced by pH.