2006Journal of Taishan Medical CollegeRequires access

Observing the clinical effect of epidural ropivacaine compounding fentanyl labor analgesia

Jingjing Zhao

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Abstract

Objective: To explore the effect of epidural ropivacaine compounding fentanyl labor analgesia and its influence on labor.Methods: With regressive analytic method,200 healthy primiparas with single fetus and term labor was randomly devided intoobserved group(100 cases) and control group(100 cases).In observed group,pregnant women accepted patient-controlled epidural analgesia(PCEA) with 0.1% ropivacaine + fentanyl(1μg/ml) while in control group who accepted nothing.Effect of analgesia 、the duration of labor、modes of delivery、neonatal Apgar score and the volume of postpartum hemorrhage in 24 hours were recorded and evaluated.Results 1) The efficient rate of labor analgesia is 96.0%.2) In the two groups,there is no significant difference in blood pressure、pulse and respiratory(P0.05).3) Compared the duration of labor of the two groups,there were significant difference in both first stage(P0.01) and total stage(P0.05) of labor while no significant difference in second stage and third stage(P0.05).4) In observed group,cases using oxytocin were more than that of control group(P0.05);there is no significant difference in instrumental delivery and natural delivery(P0.05),but there is significant difference in cesareansection(P0.05).5) Compared the two groups,there is no significant difference in neonatal Apgar score and the volume of postpartum hemorrhage in 24 hours(P0.05).Conclusions: Low concentration of epidural ropivacaine compounding fentanyl labor analgesia could shorten first stage and total stage and could decrease cesarean section rate;on the other hand,it could increase the rate of using oxytocin,but there is no negative influence on neonatal outcomes.

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Objective: To explore the effect of epidural ropivacaine compounding fentanyl labor analgesia and its influence on labor.Methods: With regressive analytic method,200 healthy primiparas with single fetus and term labor was randomly devided intoobserved group(100 cases) and control group(100 cases).In observed group,pregnant women accepted patient-controlled epidural analgesia(PCEA) with 0.1% ropivacaine + fentanyl(1μg/ml) while in control group who accepted nothing.Effect of analgesia 、the duration of labor、modes of delivery、neonatal Apgar score and the volume of postpartum hemorrhage in 24 hours were recorded and evaluated.Results 1) The efficient rate of labor analgesia is 96.0%.2) In the two groups,there is no significant difference in blood pressure、pulse and respiratory(P0.05).3) Compared the duration of labor of the two groups,there were significant difference in both first stage(P0.01) and total stage(P0.05) of labor while no significant difference in second stage and third stage(P0.05).4) In observed group,cases using oxytocin were more than that of control group(P0.05);there is no significant difference in instrumental delivery and natural delivery(P0.05),but there is significant difference in cesareansection(P0.05).5) Compared the two groups,there is no significant difference in neonatal Apgar score and the volume of postpartum hemorrhage in 24 hours(P0.05).Conclusions: Low concentration of epidural ropivacaine compounding fentanyl labor analgesia could shorten first stage and total stage and could decrease cesarean section rate;on the other hand,it could increase the rate of using oxytocin,but there is no negative influence on neonatal outcomes.

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Available abstract

Objective: To explore the effect of epidural ropivacaine compounding fentanyl labor analgesia and its influence on labor.Methods: With regressive analytic method,200 healthy primiparas with single fetus and term labor was randomly devided intoobserved group(100 cases) and control group(100 cases).In observed group,pregnant women accepted patient-controlled epidural analgesia(PCEA) with 0.1% ropivacaine + fentanyl(1μg/ml) while in control group who accepted nothing.Effect of analgesia 、the duration of labor、modes of delivery、neonatal Apgar score and the volume of postpartum hemorrhage in 24 hours were recorded and evaluated.Results 1) The efficient rate of labor analgesia is 96.0%.2) In the two groups,there is no significant difference in blood pressure、pulse and respiratory(P0.05).3) Compared the duration of labor of the two groups,there were significant difference in both first stage(P0.01) and total stage(P0.05) of labor while no significant difference in second stage and third stage(P0.05).4) In observed group,cases using oxytocin were more than that of control group(P0.05);there is no significant difference in instrumental delivery and natural delivery(P0.05),but there is significant difference in cesareansection(P0.05).5) Compared the two groups,there is no significant difference in neonatal Apgar score and the volume of postpartum hemorrhage in 24 hours(P0.05).Conclusions: Low concentration of epidural ropivacaine compounding fentanyl labor analgesia could shorten first stage and total stage and could decrease cesarean section rate;on the other hand,it could increase the rate of using oxytocin,but there is no negative influence on neonatal outcomes.

Key concepts: Ropivacaine, Fentanyl, Medicine, Anesthesia, Apgar score, Significant difference, Pregnancy, Fetus

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