2009Advances in Cardiovascular DiseasesRequires access

BNP/NT-proBNP and Diagnosis of Diastolic Heart Failure

Zhixiong Cai

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Abstract

Diastolic heart failure accounts for a high proportion of patients suffering from congestive heart failure.However,because of the lack of simple,objective methods and a unified standard for the diagnosis of diastolic heart failure,especially its early diagnosis,the rate of omission and misdiagnosis is quite high.B type natriuretic peptide and N-terminal proBNP are two objective biochemical indexes in congestive heart failure.Their diagnostic values in diastolic heart failure have been proven clinical research.Although there is controversy among scholars over their diagnostic value,we believe that with further development in research,BNP and NT-proBNP may become one of the reliable biochemical indexes respectively in the early diagnosis of diastolic heart failure.Moreover,they may have clear boundary values in the field in future,and possibly making the diagnosis of diastolic heart failure simple,accurate and reliable.

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What this paper is about

Diastolic heart failure accounts for a high proportion of patients suffering from congestive heart failure.However,because of the lack of simple,objective methods and a unified standard for the diagnosis of diastolic heart failure,especially its early diagnosis,the rate of omission and misdiagnosis is quite high.B type natriuretic peptide and N-terminal proBNP are two objective biochemical indexes in congestive heart failure.Their diagnostic values in diastolic heart failure have been proven clinical research.Although there is controversy among scholars over their diagnostic value,we believe that with further development in research,BNP and NT-proBNP may become one of the reliable biochemical indexes respectively in the early diagnosis of diastolic heart failure.Moreover,they may have clear boundary values in the field in future,and possibly making the diagnosis of diastolic heart failure simple,accurate and reliable.

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Available abstract

Diastolic heart failure accounts for a high proportion of patients suffering from congestive heart failure.However,because of the lack of simple,objective methods and a unified standard for the diagnosis of diastolic heart failure,especially its early diagnosis,the rate of omission and misdiagnosis is quite high.B type natriuretic peptide and N-terminal proBNP are two objective biochemical indexes in congestive heart failure.Their diagnostic values in diastolic heart failure have been proven clinical research.Although there is controversy among scholars over their diagnostic value,we believe that with further development in research,BNP and NT-proBNP may become one of the reliable biochemical indexes respectively in the early diagnosis of diastolic heart failure.Moreover,they may have clear boundary values in the field in future,and possibly making the diagnosis of diastolic heart failure simple,accurate and reliable.

Key concepts: Heart failure, Medicine, Diastolic heart failure, Cardiology, Diastole, Internal medicine, Natriuretic peptide, Blood pressure

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