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2004•Southern China Journal of Dermato-VenereologyRequires access

Investigation on the Therapeutic Effect of Desloratadine in Treatment of Chronic Urticaria

XU Min-hong

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Abstract

Objective:To observe the clinical efficacy and safety of desloratadine in treatment of chronic urticaria. Methods:A randomly comparative study was conducted. The patients were randomly divided into two groups:receive desloratadine (5 mg) in study group or mizolastine (10 mg) in control once daily for two weeks. Results:156 patients completed the trial,including 81 cases in desliratadine group and 75 cases in mizolasline group. The effective rate of desloratadine and mizolastine group were 88.9% and 86.6% respectively, No statistical significance was observed between two groups (P0.05) after two weeks treatment. The incidences of adverse reaction of desloratadine and mizolastine were 10.9% and 9.3% respectively, There were no statistical significance between two groups (P0.05). Conclusion:Desloratadine is an effective and safe drug in treatment of chronic urticaria.

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What this paper is about

Objective:To observe the clinical efficacy and safety of desloratadine in treatment of chronic urticaria. Methods:A randomly comparative study was conducted. The patients were randomly divided into two groups:receive desloratadine (5 mg) in study group or mizolastine (10 mg) in control once daily for two weeks. Results:156 patients completed the trial,including 81 cases in desliratadine group and 75 cases in mizolasline group. The effective rate of desloratadine and mizolastine group were 88.9% and 86.6% respectively, No statistical significance was observed between two groups (P0.05) after two weeks treatment. The incidences of adverse reaction of desloratadine and mizolastine were 10.9% and 9.3% respectively, There were no statistical significance between two groups (P0.05). Conclusion:Desloratadine is an effective and safe drug in treatment of chronic urticaria.

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Available abstract

Objective:To observe the clinical efficacy and safety of desloratadine in treatment of chronic urticaria. Methods:A randomly comparative study was conducted. The patients were randomly divided into two groups:receive desloratadine (5 mg) in study group or mizolastine (10 mg) in control once daily for two weeks. Results:156 patients completed the trial,including 81 cases in desliratadine group and 75 cases in mizolasline group. The effective rate of desloratadine and mizolastine group were 88.9% and 86.6% respectively, No statistical significance was observed between two groups (P0.05) after two weeks treatment. The incidences of adverse reaction of desloratadine and mizolastine were 10.9% and 9.3% respectively, There were no statistical significance between two groups (P0.05). Conclusion:Desloratadine is an effective and safe drug in treatment of chronic urticaria.

Key concepts: Desloratadine, Medicine, Statistical significance, Chronic idiopathic urticaria, Adverse effect, Chronic urticaria, Internal medicine, Therapeutic effect

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